Dermatitis herpetiformis and primary sclerosing cholangitis

Summary A patient with dermatitis herpetiformis (DH) developed abnormal liver function tests and was found to have histological features of primary sclerosing cholangitis (PSC) on liver biopsy. The association of DH and PSC has not been previously reported and the high incidence of phenotype HLA B8...

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Bibliographic Details
Published in:Clinical and experimental dermatology 1993-07, Vol.18 (4), p.363-365
Main Authors: LEWIS, H. M., GOLDIN, R., LEONARD, J. N.
Format: Article
Language:English
Subjects:
Bile Ducts - pathology
Biological and medical sciences
Bullous diseases of the skin
Cholangitis, Sclerosing - etiology
Cholangitis, Sclerosing - pathology
Dermatitis Herpetiformis - complications
Dermatitis Herpetiformis - pathology
Dermatology
Female
Humans
Medical sciences
Middle Aged
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Summary:Summary A patient with dermatitis herpetiformis (DH) developed abnormal liver function tests and was found to have histological features of primary sclerosing cholangitis (PSC) on liver biopsy. The association of DH and PSC has not been previously reported and the high incidence of phenotype HLA B8 and DR3 in these disorders suggests a common genetic predisposition may exist for both diseases.
ISSN:0307-6938
1365-2230
DOI:10.1111/j.1365-2230.1993.tb02219.x