Tc-99m Sestamibi and Other Agents in the Detection of Metastatic Medullary Carcinoma of the Thyroid

The 10-year survival rate for medullary carcinoma of the thyroid (MCT) is 50%; thus, good tumor-seeking radiopharmaceuticals are needed to localize foci of recurrence and metastasis during follow-up. Two patients with metastatic MCT were studied with Tl-201, l-131 MIBG, Tc-99m (V)-DMSA, and Tc-99m M...

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Published in:Clinical nuclear medicine 1993-08, Vol.18 (8), p.657-660
Main Authors: LEBOUTHILLIER, GILLES, MORAIS, JACQUES, PICARD, MICHEL, PICARD, DANIEL, CHARTRAND, RAYMONDE, DʼAMOUR, PIERRE
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Carcinoma, Medullary - diagnostic imaging
Carcinoma, Medullary - secondary
Endocrine glands. Genital system. Mammary gland
Evaluation Studies as Topic
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Lymphatic Metastasis - diagnostic imaging
Male
Medical sciences
Neoplasm Recurrence, Local - diagnostic imaging
Organotechnetium Compounds
Radionuclide investigations
Succimer
Technetium Tc 99m Dimercaptosuccinic Acid
Technetium Tc 99m Sestamibi
Thyroid Neoplasms - diagnostic imaging
Tomography, Emission-Computed, Single-Photon
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container_end_page 660
container_issue 8
container_start_page 657
container_title Clinical nuclear medicine
container_volume 18
creator LEBOUTHILLIER, GILLES
MORAIS, JACQUES
PICARD, MICHEL
PICARD, DANIEL
CHARTRAND, RAYMONDE
DʼAMOUR, PIERRE
description The 10-year survival rate for medullary carcinoma of the thyroid (MCT) is 50%; thus, good tumor-seeking radiopharmaceuticals are needed to localize foci of recurrence and metastasis during follow-up. Two patients with metastatic MCT were studied with Tl-201, l-131 MIBG, Tc-99m (V)-DMSA, and Tc-99m MIBI. A SPECT study with the latter agent allowed the visualization and precise localization of a metastatic mediastinal lymph node. More studies need to be done to evaluate the role of Tc-99m MIBI in the detection of recurrence and metastases of MCT.
doi_str_mv 10.1097/00003072-199308000-00005
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source LWW Online
subjects Adult
Aged
Biological and medical sciences
Carcinoma, Medullary - diagnostic imaging
Carcinoma, Medullary - secondary
Endocrine glands. Genital system. Mammary gland
Evaluation Studies as Topic
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Lymphatic Metastasis - diagnostic imaging
Male
Medical sciences
Neoplasm Recurrence, Local - diagnostic imaging
Organotechnetium Compounds
Radionuclide investigations
Succimer
Technetium Tc 99m Dimercaptosuccinic Acid
Technetium Tc 99m Sestamibi
Thyroid Neoplasms - diagnostic imaging
Tomography, Emission-Computed, Single-Photon
title Tc-99m Sestamibi and Other Agents in the Detection of Metastatic Medullary Carcinoma of the Thyroid
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