Role of Transfusion-mediated Viral Infections on the Lymphocyte Subset Profile in Multi-transfused Children

A total of 74 multitransfused (MT) children of beta thalassaemia major were analysed for prevalent viral markers transmitted through transfusion. A higher incidence of serologcal markers for Hepatitis B virus (HBV), cytomegalovirus (CMV) could be observed in the group of MT children compared to cont...

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Bibliographic Details
Published in:Journal of tropical pediatrics (1980) 1993-08, Vol.39 (4), p.243-250
Main Authors: Yadav, Sangita, Chattopadhya, Debashish, Prakash, Charu, Kumari, Sudershan, Vergheese, T.
Format: Article
Language:English
Subjects:
Acquired Immunodeficiency Syndrome - epidemiology
Acquired Immunodeficiency Syndrome - immunology
Adolescent
AIDS/HIV
Anemias. Hemoglobinopathies
beta-Thalassemia - epidemiology
beta-Thalassemia - immunology
Biological and medical sciences
Biomarkers
Child
Child, Preschool
cytomegalovirus
Cytomegalovirus Infections - epidemiology
Cytomegalovirus Infections - immunology
Diseases of red blood cells
Epstein-Barr virus
Female
Hematologic and hematopoietic diseases
Hepatitis B - epidemiology
Hepatitis B - immunology
hepatitis B virus
Humans
Immunoglobulin M - immunology
India - epidemiology
Leukocyte Count
Lymphocyte Subsets - immunology
Male
Medical sciences
Prevalence
Transfusion Reaction
Tropical medicine
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Summary:A total of 74 multitransfused (MT) children of beta thalassaemia major were analysed for prevalent viral markers transmitted through transfusion. A higher incidence of serologcal markers for Hepatitis B virus (HBV), cytomegalovirus (CMV) could be observed in the group of MT children compared to control group. There was a significant trend (χ2=33.4; P
ISSN:0142-6338
1465-3664
DOI:10.1093/tropej/39.4.243