High internal phase emulsion as reaction medium for precipitating brushite crystals

This present work was aimed at fabrication of brushite crystals using oil-in-water high internal phase emulsion as a reaction medium. The oil phase of more than 75 wt.% was dispersed in the continuous aqueous phase. Due to the high oil volume fraction, the oil droplets were no longer spherical but w...

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Bibliographic Details
Published in:Ceramics international 2010-07, Vol.36 (5), p.1503-1509
Main Authors: Lim, H.N., Kassim, A., Huang, N.M., Lee, K.H., Syahida, A., Chia, C.H.
Format: Article
Language:English
Subjects:
Biomedical materials
Brushes
Brushite
Ceramics
Coatings
Crystal structure
Crystals
Droplets
E. Biomedical applications
Emulsions
High internal phase emulsion
Precursors
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Summary:This present work was aimed at fabrication of brushite crystals using oil-in-water high internal phase emulsion as a reaction medium. The oil phase of more than 75 wt.% was dispersed in the continuous aqueous phase. Due to the high oil volume fraction, the oil droplets were no longer spherical but were squeezed to take the shape of polyhedral. The morphology of the crystals was influenced by the structure of the emulsion and precursor concentration. The crystals were subjected to cytotoxicity test to ensure their compatibility with synoviocytes, which are cells that line the knee joints of rabbits. The crystals were able to sustain the cells for 5 days, which manifest their potential as osteoconductive coatings.
ISSN:0272-8842
1873-3956
DOI:10.1016/j.ceramint.2010.02.029