Health-related quality of life (Nottingham Health Profile) in knee osteoarthritis: correlation with clinical variables and self-reported disability

• Published in: Rheumatology international 2010-11, Vol.30 (12), p.1595-1600
• Main Authors: Yildiz, Necmettin, Topuz, Oya, Gungen, Gonca O., Deniz, Saadet, Alkan, Hakan, Ardic, Fusun
• Format: Article
• Language: English
• Subjects: Aged; Diagnostic Self Evaluation; Disability Evaluation; Exercise Test; Female; Health Status; Humans; Knee Joint - physiopathology; Male; Medicine; Medicine & Public Health; Middle Aged; Original Article; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - physiopathology; Pain - etiology; Pain - physiopathology; Quality of Life; Range of Motion, Articular; Rheumatology; Severity of Illness Index
• ISSN: 0172-8172; 1437-160X
• DOI: 10.1007/s00296-009-1195-x

The aims of this study were to assess the health-related quality of life (HRQoL) in patients with knee osteoarthritis (OA) using the Nottingham Health Profile (NHP) and to determine its relationships with conventional clinical measures and self-reported disability. One hundred and forty patients with knee OA (104 female, 36 male, mean age 59.39 ± 7.62 years, mean disease duration 58.56 ± 56.78 months) and 40 sex and age-matched controls were included in the study. HRQoL, disability and pain were assessed using NHP, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Visual Analog Scale (VAS), respectively. Results showed that the six subgroups of the NHP revealed higher scores in the knee OA patients compared with controls ( p