Anatomical variations of the right coronary artery may be a source of difficult block and conduction recurrence in catheter ablation of common-type atrial flutter

• Published in: Europace (London, England) England), 2010-11, Vol.12 (11), p.1608-1615
• Main Authors: Klemm, Hanno U, Weber, Tim F, Johnsen, Christin, Begemann, Philipp G C, Meinertz, Thomas, Ventura, Rodolfo
• Format: Article
• Language: English
• Subjects: Aged; Anti-Arrhythmia Agents - therapeutic use; Atrial Flutter - diagnostic imaging; Atrial Flutter - drug therapy; Atrial Flutter - physiopathology; Atrial Flutter - surgery; Catheter Ablation; Coronary Vessels - anatomy & histology; Female; Heart Conduction System - physiopathology; Heart Conduction System - surgery; Humans; Male; Middle Aged; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome; Tricuspid Valve - diagnostic imaging; Tricuspid Valve - physiopathology; Tricuspid Valve - surgery; Vena Cava, Inferior - diagnostic imaging; Vena Cava, Inferior - physiopathology; Vena Cava, Inferior - surgery
• ISSN: 1099-5129; 1532-2092
• DOI: 10.1093/europace/euq320

Although Eustachian valves and recesses have been related to resistance to block, the effect of convective cooling by the right coronary artery (RCA) has not been evaluated in the clinical setting. The distance and course of the RCA in relation to the cavotricuspid isthmus (CTI) in addition to variants of CTI anatomy and the presence of Eustachian valves were analysed from computed tomography scans of 54 patients. Ablation power was titrated using a step-up protocol. Invasive follow-up was available for 34 patients. The RCA came closest to the CTI inferiorly separated by a mean of 5.3 ± 2.5 mm compared with 7.3 ± 3.3 mm septally and 5.7 ± 2.3 mm anteriorly (P < 0.01). The maximum power required for CTI block correlated inversely with the distance of the RCA to the CTI, whereas the cumulative energy was highest in the presence of recesses. Neither failure of acute block nor a higher rate of conduction recurrence could be attributed to variants of CTI anatomy or the presence of a Eustachian valve. Using multivariate analysis, a position of the RCA underneath the central part of the CTI was the only significant predictor for late conduction recurrence. These patients showed a 2.7 mm larger distance of the RCA to the tricuspid valve plane (P = 0.05). The RCA affects CTI ablation as higher power settings are required at closer distances to the ablation site. Late conduction recurrences were observed in patients with a variation of the RCA, leaving the atrioventricular groove towards the atrial aspect.