Two New Cases of Liver Angiosarcoma: History and Perspectives of Liver Angiosarcoma Among Plastic Industry Workers

In this report of two new cases of liver angiosarcoma (ASL) among plastic industry workers, the authors present the history and perspectives of this problem. The first cases of ASL have been registered since 1974, and in 1984, the European register of angiosarcoma was founded. In this register, 11 c...

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Bibliographic Details
Published in:Toxicology and industrial health 1997-09, Vol.13 (5), p.639-647
Main Authors: Hozo, Izet, Andelinovi, Šimun, Ljuti, Dragan, Bojic, Lovre, Miri, Dinko, Giunio, Lovel
Format: Article
Language:English
Subjects:
Adult
Chemical Industry
Croatia
Hemangiosarcoma - chemically induced
Humans
Liver Neoplasms - chemically induced
Male
Middle Aged
Occupational Diseases - etiology
Occupational Exposure
Plastics
Registries
Vinyl Chloride - adverse effects
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Summary:In this report of two new cases of liver angiosarcoma (ASL) among plastic industry workers, the authors present the history and perspectives of this problem. The first cases of ASL have been registered since 1974, and in 1984, the European register of angiosarcoma was founded. In this register, 11 cases of ASL and one case of haemangiopericytoma have been registeredfrom Croatia, all from a single plastics plant near Split. Two new cases ofASL (in retired autoclave cleaners, who were exposed to a concentration of 500-1000 ppm vinyl chloride monomer (VCM) during the working process) in the same plant are presented. They were detected with combined techniques ofASL detection, and both are still alive. The diagnoses have been histologically confirmed: one of them was surgically treated with segmental liver resection. The appearance of new cases of ASL confirms the perspective presented in the last report by the same authors.
ISSN:0748-2337
1477-0393
DOI:10.1177/074823379701300505