Soft tissue sarcomas of the hand and foot

A retrospective study was made of 82 soft tissue sarcomas of the hand and foot. Prognosis was related to histopathologic grade of malignancy and success or failure of local tumor control. After treatment with curative intent, low‐grade tumors gave a 5‐year survival rate of 90%, compared to 63% for h...

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Bibliographic Details
Published in:Cancer 1985-05, Vol.55 (9), p.2010-2018
Main Authors: Owens, Jay C., Shiu, Man H., Smith, Robert, Hajdu, Steven I.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Amputation
Biological and medical sciences
Child
Child, Preschool
Dermatology
Female
Foot
Hand
Humans
Male
Medical sciences
Middle Aged
Neoplasm Invasiveness
Neoplasm Metastasis
Neoplasm Recurrence, Local
Prognosis
Sarcoma - pathology
Sarcoma - surgery
Soft Tissue Neoplasms - pathology
Soft Tissue Neoplasms - surgery
Time Factors
Tumors of the skin and soft tissue. Premalignant lesions
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Summary:A retrospective study was made of 82 soft tissue sarcomas of the hand and foot. Prognosis was related to histopathologic grade of malignancy and success or failure of local tumor control. After treatment with curative intent, low‐grade tumors gave a 5‐year survival rate of 90%, compared to 63% for high‐grade tumors. Simple excision or limited amputation of the digit, hand, or foot yielded a 5‐year survival rate of 68% (15/22) and a local recurrence rate of 32%. Amputation below the elbow or knee or higher resulted in a similar survival of 68% (19/28) but no local recurrences. All patients who developed local recurrences died, except for two with low‐grade tumors and one patient lost to follow‐up. These observations indicate the need for systemic chemotherapy to prevent death from metastasis, and for effective local tumor control. Conventional radiation therapy may be difficult to apply at these sites. Innovative local treatment approaches to preserve limb function without jeopardizing tumor control merit study.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19850501)55:9<2010::AID-CNCR2820550931>3.0.CO;2-W