Rapid Diagnosis of Chlamydia psittaci Pneumonia

Two cases of Chlamydia psittaci pneumonia are presented. In each, a rapid diagnosis was made through the use of direct immunofluorescent antibody staining of respiratory secretions with monoclonal antibodies to chlamydial antigens. In one case the diagnosis was confirmed by the isolation of the caus...

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Bibliographic Details
Published in:Clinical infectious diseases 1993-09, Vol.17 (3), p.338-343
Main Authors: Oldach, David W., Gaydos, Charlotte A., Mundy, Linda M., Quinn, Thomas C.
Format: Article
Language:English
Subjects:
Antibodies
Antigens
Antigens, Bacterial - analysis
Bacterial diseases
Bacterial diseases of the respiratory system
Biological and medical sciences
Cell culture techniques
Chlamydia
Chlamydia Infections - diagnosis
Chlamydia pneumoniae
Chlamydia psittaci
Chlamydia trachomatis
Chlamydophila pneumoniae
Chlamydophila psittaci - immunology
Chlamydophila psittaci - isolation & purification
Clinical Infectious Disease Articles
Fluorescent Antibody Technique
Human bacterial diseases
Humans
Infections
Infectious diseases
Male
Medical sciences
Middle Aged
Monoclonal antibodies
Pneumonia
Pneumonia - diagnosis
Psittacosis
Sputum
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Summary:Two cases of Chlamydia psittaci pneumonia are presented. In each, a rapid diagnosis was made through the use of direct immunofluorescent antibody staining of respiratory secretions with monoclonal antibodies to chlamydial antigens. In one case the diagnosis was confirmed by the isolation of the causative organism from sputum and a pharyngeal swab. Chlamydial lipopolysac-charide was detectable in sputum from this patient in an enzyme immunoassay. Serological responses to C. psittaci, Chlamydia trachomatis, and Chlamydia pneumoniae were evaluated, and serological cross-reactivity was observed between each species. Rapid antigen detection systems for Chlamydia species that use commercially available reagents can be helpful in the evaluation of selected patient populations.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/17.3.338