Evaluation of the central dopaminergic activity in gestational hyperprolactinaemia by means of the electroretinographic technique

Electroretinography, a simple, bloodless technique commonly used in ophthalmological diagnostic practice, seems to give important informations on the level of activity of the retinal and/or other central dopaminergic systems. The Authors have employed this technique in a group of 30 normal pregnant...

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Bibliographic Details
Published in:Clinical and experimental obstetrics & gynecology 1985, Vol.12 (1-2), p.13-15
Main Authors: De Luca Brunori, I, Moggi, G, Fornaro, P, Teti, G, Murru, S, Gadducci, A, Castrogiovanni, P, Perossini, M
Format: Article
Language:English
Subjects:
Brain - physiology
Dopamine - physiology
Electroretinography
Female
Humans
Pregnancy
Prolactin - blood
Retina - physiology
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Summary:Electroretinography, a simple, bloodless technique commonly used in ophthalmological diagnostic practice, seems to give important informations on the level of activity of the retinal and/or other central dopaminergic systems. The Authors have employed this technique in a group of 30 normal pregnant women in the ninth month of gestation, in order to evaluate the dopaminergic activity in a condition of physiological hyperprolactinemia, such as pregnancy, and in a group of 25 normal nonpregnant control women. The b wave amplitude of the electroretinographic traces was significantly higher in pregnant women than in controls, suggesting an over-activity of dopaminergic systems in late pregnancy. The possible interpretations of these data are discussed.
ISSN:0390-6663