Application of contrast agents in CT and MRI (NMR) their potential in imaging of brain tumors

21 patients with clinical and CT diagnoses of intracranial tumor were studied by MRI (NMR) prior to and after administration of intravenous Gadolinium-DTPA. Resultant MRI images were compared with corresponding CT sections with respect to lesion detection, contrast enhancement, tumor delineation and...

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Bibliographic Details
Published in:Neuroradiology 1985-01, Vol.27 (2), p.164-171
Main Authors: CLAUSSEN, C, LANIADO, M, KAZNER, E, SCHÖRNER, W, FELIX, R
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Brain Neoplasms - diagnosis
Brain Neoplasms - secondary
Diatrizoate
Female
Gadolinium
Humans
Magnetic Resonance Spectroscopy
Male
Medical sciences
Meningeal Neoplasms - diagnostic imaging
Meningioma - diagnostic imaging
Middle Aged
Neurology
Neuroma, Acoustic - diagnostic imaging
Pentetic Acid
Tomography, X-Ray Computed
Tumors of the nervous system. Phacomatoses
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Summary:21 patients with clinical and CT diagnoses of intracranial tumor were studied by MRI (NMR) prior to and after administration of intravenous Gadolinium-DTPA. Resultant MRI images were compared with corresponding CT sections with respect to lesion detection, contrast enhancement, tumor delineation and visualization of perifocal edema. All intracranial lesions shown on CT were identified on MRI. Contrast enhancement in MRI images was achieved in 19 out of 21 patients, as it was also with CT. In these cases improved differentiation between tumor, perifocal edema and adjacent brain structures were obtained. In most cases sufficient visualization of perifocal edema in MRI required T2 weighted images (SE 1600/70) in addition to spin echo scans routinely performed prior to and after contrast medium (SE 400/30 or 800/30). No side effects were encountered following administration of Gadolinium-DTPA. The good tolerance and the efficacy justifies the use of Gadolinium-DTPA for contrast enhanced MRI imaging.
ISSN:0028-3940
1432-1920
DOI:10.1007/BF00343790