Mouth occlusion pressure (P0.1) in acute respiratory failure

We studied 20 unselected patients admitted to our Intensive Care Unit (ICU) suffering from acute respiratory failure (ARF), who needed mechanical ventilatory support. In all of them we followed a prospective protocol to investigate the value of mouth occlusion pressure (P0.1) as an indicator for wea...

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Bibliographic Details
Published in:Intensive care medicine 1985-05, Vol.11 (3), p.134-139
Main Authors: HERRERA, M, BLASCO, J, VENEGAS, J, BARBA, R, DOBLAS, A, MARQUEZ, E
Format: Article
Language:English
Subjects:
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Gas Analysis
Emergency and intensive respiratory care
Female
Humans
Inspiratory Capacity
Intensive care medicine
Lung Diseases, Obstructive - complications
Male
Medical sciences
Middle Aged
Pulmonary Ventilation
Residual Volume
Respiration
Respiration, Artificial
Respiratory Function Tests
Respiratory Insufficiency - etiology
Respiratory Insufficiency - physiopathology
Respiratory Insufficiency - therapy
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Summary:We studied 20 unselected patients admitted to our Intensive Care Unit (ICU) suffering from acute respiratory failure (ARF), who needed mechanical ventilatory support. In all of them we followed a prospective protocol to investigate the value of mouth occlusion pressure (P0.1) as an indicator for weaning. Fifty-two tests were classified into three groups: a need to be reconnected to mechanical ventilation (MV), stable on intermittent mandatory ventilation (IMV), or spontaneous breathing on a T-tube (TT). The results showed that at increased values of P0.1 there were more difficulties in weaning patients from MV. Seventy-eight percent (78%) of the occasions where weaning was successful, values of P0.1 were less than or equal to 4.2 cm H2O, in chronic or non-chronic patients. Eighty-nine percent (89%) of the times when P0.1 values were higher than 4.2 cm H2O the same patients required ventilatory support, total (MV) or partial (IMV). These differences were statistically significant (p less than 0.01). We conclude that the P0.1 is an easily obtained non-invasive parameter, that can contribute along with other more conventional measurements to a superior indication for weaning.
ISSN:0342-4642
1432-1238
DOI:10.1007/bf00258538