Candidemia from a Urinary Tract Source: Microbiological Aspects and Clinical Significance

Twenty-six cases of candidemia associated with a well-defined urinary tract source were retrospectively identified and reviewed. Urinary tract abnormalities were present in 23 of 26 patients (88%), 19 (73%) of whom had urinary tract obstruction. Nineteen patients had undergone urinary tract procedur...

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Bibliographic Details
Published in:Clinical infectious diseases 1993-10, Vol.17 (4), p.662-666
Main Authors: Ang, B. S. P., Telenti, A., King, B., Steckelberg, J. M., Wilson, W. R.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Amphotericin B - therapeutic use
Antifungals
Biological and medical sciences
Blood
Candida
Candidemia
Candidiasis
Candidiasis - drug therapy
Candidiasis - etiology
Clinical Infectious Disease Articles
Female
Fungemia - drug therapy
Fungemia - etiology
Human mycoses
Humans
Infections
Infectious diseases
Male
Medical sciences
Middle Aged
Mycoses
Mycoses of the urinary system
Postoperative Complications
Retrospective Studies
Stents
Treatment Outcome
Urinary bladder
Urinary tract
Urinary Tract - abnormalities
Urinary Tract Infections - complications
Urinary Tract Infections - drug therapy
Urine
Urine - microbiology
Urography
Urologic Diseases - complications
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Description
Summary:Twenty-six cases of candidemia associated with a well-defined urinary tract source were retrospectively identified and reviewed. Urinary tract abnormalities were present in 23 of 26 patients (88%), 19 (73%) of whom had urinary tract obstruction. Nineteen patients had undergone urinary tract procedures before the onset of candidemia. Episodes of candidemia were brief and low-grade in intensity (median duration, 1 day; median colony count, 1.5 cfu/10 mL of blood). Only eight patients (31%) received ⩾500 mg of amphotericin B. There were five in-hospital deaths (19%); two of these deaths were attributed to candidiasis. No late complications of candidemia were documented for the surviving patients. Patients with urologic pathology and candiduria who undergo surgery or manipulation of the urinary tract are at significant risk for candidemia, and further studies should examine the issue of administration of prophylaxis to this group.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/17.4.662