The in-vitro activity of some antimicrobial agents against methicillin-resistant Staphylococcus aureus

A total of 185 strains of methicillin resistant Staphylococcus aureus was investigated for sensitivity to five other antimicrobial agents. The vast majoriy of these strains were also resistant to gentamicin and fusidic acid. Rifampicin was the most active drug tested (MIC90, 0·007 mg/l), while two n...

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 1985-03, Vol.15 (3), p.291-295
Main Authors: Moorhouse, E.C., Mulvihill, T. E., Jones, L., Mooney, D., Falkiner, F.R., Keane, C.T.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Ciprofloxacin
Fusidic Acid - pharmacology
Gentamicins - pharmacology
Glycopeptides - pharmacology
Medical sciences
Methicillin - pharmacology
Microbial Sensitivity Tests
Penicillin Resistance
Pharmacology. Drug treatments
Quinolines - pharmacology
Rifampin - pharmacology
Staphylococcus aureus - drug effects
Staphylococcus Phages - classification
Teicoplanin
Vancomycin - pharmacology
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Summary:A total of 185 strains of methicillin resistant Staphylococcus aureus was investigated for sensitivity to five other antimicrobial agents. The vast majoriy of these strains were also resistant to gentamicin and fusidic acid. Rifampicin was the most active drug tested (MIC90, 0·007 mg/l), while two newer compounds teichomycin and ciprofloxacin showed equal and appreciable activity (MIC90, 0·5 mg/l)
ISSN:0305-7453
1460-2091
DOI:10.1093/jac/15.3.291