Endocrine‐metabolic response to abdominal aortic surgery: A randomized trial of general anesthesia versus general plus epidural anesthesia

The influence of epidural anesthesia on the endocrine‐metabolic response following abdominal aortic reconstruction was studied in a prospective randomized trial. Cortisol and catecholamine responses and nitrogen balance were measured in two groups of five patients receiving general anesthesia only (...

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Bibliographic Details
Published in:World journal of surgery 1993-09, Vol.17 (5), p.601-606
Main Authors: Smeets, Harm J., Kievit, Job, Dulfer, Frans T., van Kleef, Jack W.
Format: Article
Language:English
Subjects:
Aged
Anesthesia, Epidural
Anesthesia, General
Aorta, Abdominal - surgery
Bupivacaine
Catecholamine Response
Catecholamines - metabolism
Cortisol
Epidural Anesthesia
Humans
Hydrocortisone - metabolism
Male
Middle Aged
Nitrogen - metabolism
Nitrogen Balance
Prospective Studies
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Summary:The influence of epidural anesthesia on the endocrine‐metabolic response following abdominal aortic reconstruction was studied in a prospective randomized trial. Cortisol and catecholamine responses and nitrogen balance were measured in two groups of five patients receiving general anesthesia only (group 1) or general anesthesia combined with epidural bupivacaine (group 2). The study lasted from preoperatively until the first postoperative day. At 2100 hours on the day of surgery serum cortisol concentrations were higher in group 1 than in group 2 (1.41 versus 0.82 μmol/L; p
ISSN:0364-2313
1432-2323
DOI:10.1007/BF01659119