NITROUS OXIDE AND WOUND HEALING

Following a paravertebral surgical incision, mature, female rats under ether anaesthesia were exposed to either 3% nitrous oxide, continuously for 48 h, or 50% nitrous oxide, 4 h each day for 7 days. For each exposure group, a similar number of rats was exposed to atmospheres containing no nitrous o...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1985-06, Vol.57 (6), p.621-623
Main Authors: ALIGIE, T.A., SETH, A., BARBENEL, J.C., GALLOWAY, D.J., GRAY, W.M., SPENCE, A.A.
Format: Article
Language:English
Subjects:
Anesthetics. Neuromuscular blocking agents
Animals
Biological and medical sciences
Female
Medical sciences
Neuropharmacology
Nitrous Oxide - pharmacology
Pharmacology. Drug treatments
Rats
Tensile Strength - drug effects
Time Factors
Wound Healing - drug effects
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Summary:Following a paravertebral surgical incision, mature, female rats under ether anaesthesia were exposed to either 3% nitrous oxide, continuously for 48 h, or 50% nitrous oxide, 4 h each day for 7 days. For each exposure group, a similar number of rats was exposed to atmospheres containing no nitrous oxide. Wound healing was assessed by measurement of the breaking strengths of wound samples. No statistically significant influence on breaking strength could be attributed to nitrous oxide following either exposure sequence.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/57.6.621