Radionuclide migration through the genital tract in infertile women with endometriosis

The migration of radionuclide through the genital tract was observed, comparing 20 patients with endometriosis and infertility with a control group of 23 infertile patients who had a normal pelvis. All patients had patent tubes at laparoscopy and chromopertubation, performed in both groups for the i...

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Bibliographic Details
Published in:Human reproduction (Oxford) 1993-11, Vol.8 (11), p.1910-1914
Main Authors: MCQUEEN, D, MCKILLOP, J. H, GRAY, H. W, CALLAGHAN, M, MONAGHAN, C, BESSENT, R. G
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Endometriosis - complications
Endometriosis - diagnostic imaging
Fallopian Tube Patency Tests
Fallopian Tubes - diagnostic imaging
Female
Female genital diseases
Genitalia, Female - diagnostic imaging
Gynecology. Andrology. Obstetrics
Humans
Infertility, Female - diagnostic imaging
Infertility, Female - etiology
Medical sciences
Microspheres
Non tumoral diseases
Peritoneal Cavity - diagnostic imaging
Radionuclide Imaging
Technetium
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Summary:The migration of radionuclide through the genital tract was observed, comparing 20 patients with endometriosis and infertility with a control group of 23 infertile patients who had a normal pelvis. All patients had patent tubes at laparoscopy and chromopertubation, performed in both groups for the investigation of infertility and to diagnose the presence and extent of endometriosis. A radionuclide tubal test, using human albumin microspheres labelled with 99m-technetium (99mTc) was subsequently undertaken to observe the extent of genital tract migration of radionuclide to uterus, Fallopian tube and peritoneal cavity. The results show that radionuclide migration to the peritoneal cavity was impaired in patients with endometriosis, compared with the control group (30 versus 83%, respectively; P < 0.001). There was no relationship between migration and the severity of endometriosis. We conclude that impaired tubal function may be a cause of infertility in some patients with endometriosis.
ISSN:0268-1161
1460-2350
DOI:10.1093/oxfordjournals.humrep.a137959