Actinic reticuloid simulating Sézary syndrome: report of two cases

A report is given on two male patients who showed all the main characteristics of Sézary syndrome (SS). When phototested, however, they proved to be extremely photosensitive, which suggested a diagnosis of actinic reticuloid (AR). This was supported by the predominance in blood and skin specimens of...

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Bibliographic Details
Published in:Archives of Dermatological Research 1985-02, Vol.277 (3), p.159-166
Main Authors: TOONSTRA, J, VAN WEELDEN, H, MEYLING, F. H. J. G, VAN DER PUTTE, S. C. J, SCHIERE, S. I. M, DE LA FAILLE, H. B
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Biopsy
Dermatitis, Exfoliative - pathology
Diagnosis, Differential
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Leukocyte Count
Lymphocytes - pathology
Male
Medical sciences
Middle Aged
Photosensitivity Disorders - pathology
Sezary Syndrome - pathology
Skin - pathology
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Summary:A report is given on two male patients who showed all the main characteristics of Sézary syndrome (SS). When phototested, however, they proved to be extremely photosensitive, which suggested a diagnosis of actinic reticuloid (AR). This was supported by the predominance in blood and skin specimens of lymphoid cells with a suppressor/cytotoxic phenotype, the absence of clonal cell proliferation and a benign clinical course. Differential diagnostic problems of SS and erythrodermic AR are discussed.
ISSN:0340-3696
1432-069X
DOI:10.1007/BF00404310