ABO hemolytic disease of the fetus and newborn: an iatrogenic complication of heterologous assisted reproductive technology-induced pregnancy

BACKGROUND: ABO hemolytic disease of the fetus and newborn (ABO HDFN) may manifest itself in cases of mothers belonging to blood group O and newborns of groups A or B and more frequently in group A and less so in group B. CASE STUDY: The case subjects are twin‐birth newborns with ABO HDFN, of group...

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Bibliographic Details
Published in:Transfusion (Philadelphia, Pa.) Pa.), 2010-10, Vol.50 (10), p.2102-2104
Main Authors: Zuppa, Antonio Alberto, Cardiello, Valentina, Lai, Marco, Cataldi, Luigi, D'Andrea, Vito, Romagnoli, Costantino
Format: Article
Language:English
Subjects:
ABO Blood-Group System - blood
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Bilirubin - blood
Biological and medical sciences
Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis
Drug toxicity and drugs side effects treatment
Erythroblastosis, Fetal - blood
Erythroblastosis, Fetal - diagnosis
Female
Humans
Infant, Newborn
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Pregnancy
Reproductive Techniques, Assisted - adverse effects
Toxicity: blood
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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Summary:BACKGROUND: ABO hemolytic disease of the fetus and newborn (ABO HDFN) may manifest itself in cases of mothers belonging to blood group O and newborns of groups A or B and more frequently in group A and less so in group B. CASE STUDY: The case subjects are twin‐birth newborns with ABO HDFN, of group AB born to a mother of group O. These cases of ABO HDFN prove inconsistent with Mendel's law of segregation. RESULTS AND CONCLUSION: This case study finds its explanation in new methods of assisted reproduction, particularly heterologous in vitro fertilization with ovodonation.
ISSN:0041-1132
1537-2995
DOI:10.1111/j.1537-2995.2010.02698.x