Lithium prophylaxis of recurrent affective disorders

The mode of action of lithium is reviewed in the light of advances in the understanding of calcium channelling and calmodulin-activated Ca ATPase. The relevance to changes in receptor sensitivity is discussed.

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Bibliographic Details
Published in:Journal of affective disorders 1985-05, Vol.8 (3), p.259-265
Main Author: Glen, A.I.M.
Format: Article
Language:English
Subjects:
Adenosine Triphosphatases - blood
Amine hypothesis
Animals
Biological and medical sciences
Bipolar Disorder - enzymology
Bipolar Disorder - genetics
Bipolar Disorder - prevention & control
Bipolar manic depression
Calcium - blood
Calcium-Binding Proteins - blood
Calmodulin - blood
Circadian Rhythm - drug effects
Depression
General aspects
Humans
Ion Channels - drug effects
Latitude
Lithium - therapeutic use
Mania
Medical sciences
Neuropharmacology
Parathyroid Hormone - blood
Pharmacology. Drug treatments
Receptors, Neurotransmitter - drug effects
Time of year
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Description
Summary:The mode of action of lithium is reviewed in the light of advances in the understanding of calcium channelling and calmodulin-activated Ca ATPase. The relevance to changes in receptor sensitivity is discussed.
ISSN:0165-0327
1573-2517
DOI:10.1016/0165-0327(85)90024-2