EFFECT OF DIABETES MELLITUS ON THE CARDIOVASCULAR RESPONSES TO INDUCTION OF ANAESTHESIA AND TRACHEAL INTUBATION

We have compared cardiovascular responses to induction of anaesthesia and to tracheal intubation after propofol 2.5mg kg−1 and pancuronium 0.1 mg kg−1 in 10 diabetic and 10 matched, non-diabetic (control) ASA I patients. Anaesthesia was maintained with 0.8% enflurane and 50% nitrous oxide in oxygen,...

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Bibliographic Details
Published in:British Journal of Anaesthesia 1993-08, Vol.71 (2), p.258-261
Main Authors: VOHRA, A., KUMAR, S., CHARLTON, A.J., OLUKOGA, A.O., BOULTON, A.J.M., McLEOD, D.
Format: Article
Language:English
Subjects:
Adult
Aged
Anaesthetics
Anaesthetics, intravenous: propofol
Anesthesia
Anesthesia depending on patient's condition
Anesthesia, Inhalation
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Cardiovascular System - physiopathology
Complications: diabetes
Complications: diabetes, neuropathy
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - physiopathology
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - physiopathology
Enflurane
Humans
intravenous: propofol
Intubation, Intratracheal
Intubation: complications
Medical sciences
Middle Aged
neuropathy
Nitrous Oxide
Vitrectomy
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Summary:We have compared cardiovascular responses to induction of anaesthesia and to tracheal intubation after propofol 2.5mg kg−1 and pancuronium 0.1 mg kg−1 in 10 diabetic and 10 matched, non-diabetic (control) ASA I patients. Anaesthesia was maintained with 0.8% enflurane and 50% nitrous oxide in oxygen, with assisted ventilation. The trachea was intubated 3 min after induction of anaesthesia. All 10 diabetic patients (but no controls) had abnormal autonomic function when tested on the day before surgery. There was no difference between the two groups in the preinduction cardiovascular state. Mean arterial pressure and vascular resistance decreased after induction in each group (P
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/71.2.258