Blood pressure and left ventricular mass in subjects with type 2 diabetes and gingivitis or chronic periodontitis

• Published in: Journal of clinical periodontology 2010-10, Vol.37 (10), p.875-880
• Main Authors: Franek, Edward, Napora, Magdalena, Blach, Anna, Budlewski, Tadeusz, Gozdowski, Dariusz, Jedynasty, Krystyna, Krajewski, Jarosław, Gorska, Renata
• Format: Article
• Language: English
• Subjects: Adult; Aged; Analysis of Variance; Biological and medical sciences; blood pressure; cardiovascular; Case-Control Studies; Chi-Square Distribution; Chronic Periodontitis - complications; Chronic Periodontitis - pathology; Chronic Periodontitis - physiopathology; Dentistry; diabetes; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - pathology; Diabetes Mellitus, Type 2 - physiopathology; Diabetes. Impaired glucose tolerance; Echocardiography; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Female; Gingivitis - complications; Gingivitis - pathology; Gingivitis - physiopathology; heart; Humans; Hypertension - etiology; Hypertrophy, Left Ventricular - etiology; Male; Medical sciences; Middle Aged; Non tumoral diseases; Otorhinolaryngology. Stomatology; periodontal disease; Periodontal Diseases - classification; Statistics, Nonparametric
• ISSN: 0303-6979; 1600-051X
• DOI: 10.1111/j.1600-051X.2010.01613.x

Franek E, Napora M, Blach A, Budlewski T, Gozdowski D, Jedynasty K, Krajewski J, Gorska R. Blood pressure and left ventricular mass in subjects with type 2 diabetes and gingivitis or chronic periodontitis. J Clin Periodontol 2010; 37: 875–880. doi: 10.1111/j.1600‐051X.2010.01613.x. Introduction: This study aimed to answer the question of whether chronic periodontitis in subjects with type 2 diabetes mellitus is associated with increased left ventricular mass (LVM) and systemic and central blood pressure (CBP). Material and Methods: One hundred and fifty‐five subjects with type 2 diabetes (67 F, 88 M, mean age 61.1±6.9 years, BMI 32.7±5.7 kg/m2) were divided according to their periodontal status into biofilm–gingival interface – healthy (BGI‐H, 14 subjects), BGI‐gingivitis (BGI‐G, 119 subjects) and BGI‐periodontitis (BGI‐P, 22 subjects) groups. In all subjects, LVM, systemic and CBP were measured. The LVM index (LVMI) was calculated. Results: (1) BGI‐P and BGI‐G subjects, respectively, had higher (mean; 95% CI) LVM (238.6 g; 206.6–267.4 and 222.8 g; 207.0–238.2) versus BGI‐H subjects (170.3 g; 125.5–217.8).
(2) BGI‐P and BGI‐G subjects, respectively, had higher (mean; 95% CI) LVM1 (95.2 g/m2; 82.9–107.4) and 87.8 g/m2; 81.5–94.1) versus BGI‐H subjects (63.7 g/m2; 45.2‐62.3).
(3) BGI‐P subjects had higher central and systemic systolic and diastolic blood pressure than subjects from BGI‐G and BGI‐H groups. Conclusion: In subjects with type 2 diabetes, periodontitis and gingivitis are associated with increased LVM and periodontitis is associated with increased central and systemic blood pressure.