Mys , a family of mammalian transposable elements isolated by phylogenetic screening

It has recently been demonstrated both emperically 1–3 and mathematically 4 that transposable elements may spread rapidly throughout a population once introduced even when they dramatically reduce the fitness of individuals that carry them. Such events result in pronounced differences in the phyloge...

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Bibliographic Details
Published in:Nature (London) 1985-09, Vol.317 (6032), p.77-81
Main Authors: Wichman, Holly A, Potter, S. Steven, Pine, Daniel S
Format: Article
Language:English
Subjects:
Animals
Base Sequence
Biological and medical sciences
Biological evolution
DNA Restriction Enzymes
DNA Transposable Elements
Fundamental and applied biological sciences. Psychology
Genes
Genetics of eukaryotes. Biological and molecular evolution
Humanities and Social Sciences
letter
Mice
multidisciplinary
Muridae
Nucleic Acid Hybridization
Peromyscus
Peromyscus leucopus
Phylogeny
Science
Science (multidisciplinary)
Species Specificity
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Summary:It has recently been demonstrated both emperically 1–3 and mathematically 4 that transposable elements may spread rapidly throughout a population once introduced even when they dramatically reduce the fitness of individuals that carry them. Such events result in pronounced differences in the phylogenetic distribution of genetic elements capable of rapid genome invasion. Using a simple and general procedure to screen the genome of the white footed mouse Peromyscus leucopus , we have isolated a family of retrovirus-like elements which is apparently absent from the genome of the house mouse Mus domesticus . Here, we report this procedure and an analysis of the organization, phylogenetic distribution and sequence of this family of transposable elements.
ISSN:0028-0836
1476-4687
DOI:10.1038/317077a0