RIP3 and AtKinesin-13A – A novel interaction linking Rho proteins of plants to microtubules

RIP3 belongs to a group of recently identified proteins, classified as the ICR/RIP family whose members were described to interact with Rho proteins of plants (ROPs). Our in vivo and in vitro data demonstrate that RIP3 is a true ROP effector, interacting specifically with the active form of ROPs. We...

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Bibliographic Details
Published in:European journal of cell biology 2010-12, Vol.89 (12), p.906-916
Main Authors: Mucha, Elena, Hoefle, Caroline, Hückelhoven, Ralph, Berken, Antje
Format: Article
Language:English
Subjects:
Arabidopsis - metabolism
Arabidopsis Proteins - metabolism
AtKinesin-13A
Calorimetry
Chromatography, Gel
Cytoskeleton
Effector
Fluorescence Resonance Energy Transfer
ICR
Microtubule
Microtubules - metabolism
Plant
Polar growth
Protein Binding
Rho
RIP
ROP
Two-Hybrid System Techniques
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Summary:RIP3 belongs to a group of recently identified proteins, classified as the ICR/RIP family whose members were described to interact with Rho proteins of plants (ROPs). Our in vivo and in vitro data demonstrate that RIP3 is a true ROP effector, interacting specifically with the active form of ROPs. We found that RIP3 has properties and cellular roles different from the previously described RIP family member ICR1/RIP1. We show that RIP3 is localized at microtubules and interacts with the kinesin-13 family member AtKinesin-13A, suggesting a role for RIP3 in microtubule reorganization and a possible function in ROP-regulated polar growth.
ISSN:0171-9335
1618-1298
DOI:10.1016/j.ejcb.2010.08.003