Spontaneous twin cervico-isthmic pregnancy in a grand multiparous woman

Cervico‐isthmic pregnancy is a rare form of ectopic pregnancy and is defined as the implantation of a fertilized ovum in the cervico‐isthmic portion. The cause is unknown; local pathology related to previous cervical or uterine surgery may play a role, given an apparent association with a prior hist...

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Bibliographic Details
Published in:The journal of obstetrics and gynaecology research 2010-10, Vol.36 (5), p.1112-1115
Main Authors: Cetin, Meral, Yildiz, Caglar, Yenicesu, Ayse G. I., Cetin, Ali
Format: Article
Language:English
Subjects:
Abortion, Induced
Adult
cervico-isthmic twin pregnancy
Cervix Uteri - diagnostic imaging
Female
Humans
Methotrexate
Pregnancy
Pregnancy Trimester, First
Pregnancy, Ectopic - diagnostic imaging
Pregnancy, Multiple
transvaginal ultrasonography
Ultrasonography, Prenatal
β-human chorionic gonadotrophin
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Summary:Cervico‐isthmic pregnancy is a rare form of ectopic pregnancy and is defined as the implantation of a fertilized ovum in the cervico‐isthmic portion. The cause is unknown; local pathology related to previous cervical or uterine surgery may play a role, given an apparent association with a prior history of curettage or cesarean delivery. Transvaginal ultrasonography and β‐human chorionic gonadotrophin assays are useful for diagnosis. Here we report a case of spontaneous twin cervico‐isthmic pregnancy in a grand multiparous patient who was diagnosed early in the first trimester with transvaginal ultrasonography. The pregnancy was terminated successfully with methotrexate. Methotrexate seems to be most successful at early gestational ages.
ISSN:1341-8076
1447-0756
DOI:10.1111/j.1447-0756.2010.01256.x