Waist Circumference Moderates the Association Between Marital Stress and C-reactive Protein in Middle-Aged Healthy Women

The relationships among stress, obesity, and inflammation in women remain unclear. This study examined the relationships among marital stress, waist circumference, and C-reactive protein (CRP) in 201 healthy women from the Stockholm Female Coronary Risk Study. We tested whether marital stress was as...

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Bibliographic Details
Published in:Annals of behavioral medicine 2010-12, Vol.40 (3), p.258-264
Main Authors: Shen, Biing-Jiun, Farrell, Kristen A., Penedo, Frank J., Schneiderman, Neil, Orth-Gomer, Kristina
Format: Article
Language:English
Subjects:
Blood Pressure
C-Reactive Protein - metabolism
Family Conflict
Family Medicine
Female
General Practice
Health Psychology
Humans
Inflammation - blood
Marriage
Medicine
Medicine & Public Health
Middle Aged
Obesity
Obesity - blood
Original Article
Proteins
Regression Analysis
Risk Factors
Stress
Surveys and Questionnaires
Waist Circumference
Womens health
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Summary:The relationships among stress, obesity, and inflammation in women remain unclear. This study examined the relationships among marital stress, waist circumference, and C-reactive protein (CRP) in 201 healthy women from the Stockholm Female Coronary Risk Study. We tested whether marital stress was associated with CRP and whether this association was moderated by waist circumference. Hierarchical multiple regression revealed that after adjusting for age, occupation status, fasting glucose, apolipoprotein A1, apolipoprotein B, blood pressure, smoking, and menopausal status, marital stress was not directly associated with CRP. However, waist circumference significantly moderated the association between marital stress and CRP ( p  = 0.012) such that marital stress was significantly associated with higher CRP among women with larger waist circumferences but not in those with smaller waists. More obese women may be particularly vulnerable to the effects of marital stress by manifesting higher inflammation.
ISSN:0883-6612
1532-4796
DOI:10.1007/s12160-010-9211-7