Inflammatory bowel disease of mice—and men?

Although the findings from an examination of inflammatory bowel disease in mice cannot be related directly to human inflammatory bowel disease, some of the parallels in pathological features and clinical presentation are highly suggestive that human disease is an abnormal response to a normal antige...

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Bibliographic Details
Published in:The Lancet (British edition) 1994-01, Vol.343 (8890), p.130-131
Main Authors: Macpherson, AndrewJ.S., Khoo, UiYen, Bjarnason, Ingvar
Format: Article
Language:English
Subjects:
Animals
Antigens
Atherosclerosis
Cardiovascular disease
Cholesterol
Cytokines
Disease
Disease Models, Animal
Genes
Heart
Humans
Immune system
Inflammation
Inflammatory bowel disease
Inflammatory bowel diseases
Inflammatory Bowel Diseases - immunology
Intestine
Large intestine
Lipoproteins
Lymphocytes
Medical research
Men
Mice
Mice, Transgenic - immunology
Mortality
Pathogens
Pathology
Rodents
Sexes
Womens health
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Description
Summary:Although the findings from an examination of inflammatory bowel disease in mice cannot be related directly to human inflammatory bowel disease, some of the parallels in pathological features and clinical presentation are highly suggestive that human disease is an abnormal response to a normal antigenic stimulus.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(94)90928-8