Obesity as a Risk Factor for Osteoarthritis of the Hand and Wrist: A Prospective Study

The Tecumseh Community Health Study provides an opportunity to investigate the role of obesity in the etiology of osteoarthritis. This longitudinal study, conducted in Tecumseh, Michigan, began in 1962 with baseline examinations of clinical, biochemical, and radiologic characteristics. A 1985 reexam...

Full description

Saved in:
Bibliographic Details
Published in:American journal of epidemiology 1994-01, Vol.139 (2), p.119-129
Main Authors: Carman, Wendy J., Sowers, MaryFran, Hawthorne, Victor M., Weissfeld, Lisa A.
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Biological and medical sciences
Body Mass Index
cohort studies
Diseases of the osteoarticular system
Female
Hand
Humans
Incidence
Longitudinal Studies
Male
Medical sciences
Middle Aged
obesity
Obesity - complications
Osteoarthritis
Osteoarthritis - epidemiology
Osteoarthritis - etiology
Prospective Studies
Risk Factors
Sex Factors
wrist
Wrist Joint
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The Tecumseh Community Health Study provides an opportunity to investigate the role of obesity in the etiology of osteoarthritis. This longitudinal study, conducted in Tecumseh, Michigan, began in 1962 with baseline examinations of clinical, biochemical, and radiologic characteristics. A 1985 reexamination of the cohort characterized Osteoarthritis status in 1,276 participants, 588 males and 688 females, who were aged 50–74 years at this follow-up. Baseline obesity, as measured by an index of relative weight, was found to be significantly associated with the 23-year incidence of osteo-arthritis of the hands among subjects disease free at baseline. Greater baseline relative weight was also associated with greater subsequent severity of osteoarthritis of the hands. The difference between baseline and follow-up weight values was not significantly associated with the incidence of osteoarthritis of the hands. Furthermore, there was no evidence that development of osteoarthritis subsequently led to increased incidence of obesity.
ISSN:0002-9262
1476-6256
DOI:10.1093/oxfordjournals.aje.a116974