Somatostatin in eating disorders

• Published in: The International journal of eating disorders 1994, Vol.15 (1), p.99-102
• Main Authors: Pirke, Karl M., Frieß, Elisabeth, Kellner, Michael B., Krieg, Jürgen-C., Fichter, Manfred M.
• Format: Article
• Language: English
• Subjects: Adult; Adult and adolescent clinical studies; Anorexia nervosa; Anorexia Nervosa - blood; Anorexia Nervosa - diagnosis; apetito; appetit; appetite; Biological and medical sciences; blood; caract micromorfologicas del suelo; corps gras; diet; dieta; digestive disorders; Eating behavior disorders; Energy Intake; experimentacion; experimentation; fats; Female; femme; grasas; hombres; homme; Humans; Insulin - blood; Medical sciences; men; mujeres; Obesity - blood; Obesity - diagnosis; overweight; proteinas; proteine; proteins; Psychiatric Status Rating Scales; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Radioimmunoassay; regime alimentaire; sang; sangre; sobrepeso; soil micromorphological features; somatostatin; Somatostatin - blood; somatostatina; somatostatine; surpoids; trait micromorphologique du sol; trastornos digestivos; trouble digestif; women
• ISSN: 0276-3478; 1098-108X
• DOI: 10.1002/1098-108X(199401)15:1<99::AID-EAT2260150112>3.0.CO;2-X

Somatostatin concentrations in plasma were measured before and after a standardized fat and protein-rich fluid test meal in patients with anorexia nervosa, weight-recovered anorectic patients, obese women, and healthy controls. Somatostatin was significantly elevated in all four groups after the test meals. Hormone levels remained elevated for up to 100 min after the test meal. The area under the response curve was significantly higher (p