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Measurement of cerebral blood flow during xenon inhalation as measured by the microspheres method

Measurements of cerebral blood flow (CBF) were performed using the microsphere technique in non-human primates (baboons) to assess the effect of non-radioactive xenon gas inhalation on CBF. Blood flows in small tissue volumes (approximately 1 cm3) were directly measured before and during the inhalat...

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Bibliographic Details
Published in:Stroke (1970) 1985-09, Vol.16 (5), p.871-874
Main Authors: Gur, D, Yonas, H, Jackson, D L, Wolfson, Jr, S K, Rockette, H, Good, W F, Maitz, G S, Cook, E E, Arena, V C
Format: Article
Language:English
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Summary:Measurements of cerebral blood flow (CBF) were performed using the microsphere technique in non-human primates (baboons) to assess the effect of non-radioactive xenon gas inhalation on CBF. Blood flows in small tissue volumes (approximately 1 cm3) were directly measured before and during the inhalation of xenon/oxygen gas mixtures. The results of these studies demonstrated that when inhaled in relatively high concentrations, xenon gas does increase CBF, but the changes are more global than tissue-specific. The problems and limitations of such evaluations are discussed.
ISSN:0039-2499
1524-4628
DOI:10.1161/01.str.16.5.871