Efficacy of preoperative antimicrobial skin preparation solutions on biofilm bacteria

RESEARCH ON THE MEDICAL EFFICACY of topical antimicrobials and antibiotics against infections has focused largely on the effect on free-floating, planktonic bacteria. IN THE PRESENCE OF nonbiological surfaces (eg, catheters, prosthetic devices, biomaterials), however, bacteria form highly complex bi...

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Bibliographic Details
Published in:AORN journal 2005-03, Vol.81 (3), p.492-501; quiz 503-6
Main Author: Paulson, Daryl S
Format: Article
Language:English
Subjects:
Anti-Infective Agents, Local - pharmacology
Bacteria
Bacteria - drug effects
Biofilms
Biofilms - drug effects
Catheters, Indwelling
Equipment Contamination - prevention & control
Infections
Medical treatment
Nursing
Perioperative Nursing
Preoperative Care - standards
Skin
Solutions
Treatment Outcome
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Summary:RESEARCH ON THE MEDICAL EFFICACY of topical antimicrobials and antibiotics against infections has focused largely on the effect on free-floating, planktonic bacteria. IN THE PRESENCE OF nonbiological surfaces (eg, catheters, prosthetic devices, biomaterials), however, bacteria form highly complex biofilm systems that resist traditional medical treatment. BACTERIAL PATHOGENS commonly found in chronic infections in both the planktonic and biofilm state were challenged with a variety of commonly used topical antimicrobial formulations. BIOFILM BACTERIA were shown to be more resistant to killing than planktonic bacteria. Antimicrobial skin preparation times were adequate to significantly reduce bacterial populations protected in biofilms.
ISSN:0001-2092
1878-0369