Headspace analyses of 2H labeling of acetone: Enabling studies of fatty acid oxidation in vivo

We demonstrate that one can measure low levels of 2H labeling (e.g.,

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Bibliographic Details
Published in:Analytical biochemistry 2011, Vol.408 (2), p.351-353
Main Authors: Mahsut, Ablatt, Wang, Sheng-Ping, McLaren, David G., Bhat, Gowri, Herath, Kithsiri, Miller, Paul L., Hubbard, Brian K., Johns, Douglas G., Previs, Stephen F., Roddy, Thomas P.
Format: Article
Language:English
Subjects:
acetone
Acetone - analysis
Animals
beta oxidation
deuterium
Deuterium - chemistry
Deuterium Exchange Measurement
fatty acids
Fatty Acids - chemistry
gas chromatography
Gas Chromatography-Mass Spectrometry - methods
headspace analysis
Isotope Labeling
mass spectrometry
Mice
Oxidation-Reduction
quantitative analysis
rodents
stable isotopes
Water - chemistry
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Description
Summary:We demonstrate that one can measure low levels of 2H labeling (e.g.,
ISSN:0003-2697
1096-0309
DOI:10.1016/j.ab.2010.09.016