Genomic Imprinting, DNA Methylation, and Cancer

Genomic imprinting is a reversible modification of DNA that causes differential expression of homologous chromosomes or genes. Evidence for genomic imprinting in humans and the effects on humans when genetic imprints are altered are discussed.

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1994-05, Vol.86 (10), p.753-759
Main Authors: Rainier, Shirley, Feinberg, Andrew P.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cancer
Carcinogenesis, carcinogens and anticarcinogens
carcinoma
Deoxyribonucleic acid
DNA
DNA, Neoplasm - metabolism
Gene Expression Regulation, Neoplastic
General aspects
Genetics
genomic imprinting
Humans
man
Medical research
Medical sciences
Methylation
Mutation
Neoplasms - genetics
Neoplasms - metabolism
Tumors
Citations: Items that cite this one
Online Access:Get full text
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Description
Summary:Genomic imprinting is a reversible modification of DNA that causes differential expression of homologous chromosomes or genes. Evidence for genomic imprinting in humans and the effects on humans when genetic imprints are altered are discussed.
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/86.10.753