Clinical Comparison of Technetium-99m-N,Nʼ-bis(Mercaptoacetyl)-2,3-Diaminopropanoate with Technetium-99m DTPA for Renal Imaging

We studied 14 patients having serum creatinines of 1.0 to 12.8 mg/dl with either Tc-99m-N,Nʼ-bis (mercaptoacetyl)-2,3-diaminopropanoate (CO2-DADS) or Tc-99m DTPA, and within 48 hours with the other agent. Analog and digital images of the kidneys and bladder were acquired for 30 minutes after injecti...

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Bibliographic Details
Published in:Clinical nuclear medicine 1985-11, Vol.10 (11), p.810-813
Main Authors: KUNI, CHRISTOPHER C, KLINGENSMITH, WILLIAM C, FRITZBERG, A R, SPITZER, V M, LATTEIER, JAMES L
Format: Article
Language:English
Subjects:
Alanine - analogs & derivatives
beta-Alanine - analogs & derivatives
Biological and medical sciences
Humans
Investigative techniques, diagnostic techniques (general aspects)
Kidney - diagnostic imaging
Kidney Diseases - diagnostic imaging
Medical sciences
Organotechnetium Compounds
Pentetic Acid
Radionuclide Imaging
Radionuclide investigations
Technetium
Technetium Tc 99m Pentetate
Time Factors
Urinary Bladder - diagnostic imaging
Urinary system
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Summary:We studied 14 patients having serum creatinines of 1.0 to 12.8 mg/dl with either Tc-99m-N,Nʼ-bis (mercaptoacetyl)-2,3-diaminopropanoate (CO2-DADS) or Tc-99m DTPA, and within 48 hours with the other agent. Analog and digital images of the kidneys and bladder were acquired for 30 minutes after injection and after voiding. The kidney-to-background ratio at 3 minutes for Tc-99m CO2-DADS was 2.01 ± 0.79 (mean ± SD) times that for Tc-99m DTPA (P
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-198511000-00015