Advanced Colorectal Adenocarcinoma: Treatment With Amonafide

A study in which 34 ambulatory patients with measurable, advanced colorectal adenocarcinoma were treated with amonafide is described in a letter to the editor. It was discovered that amonafide has insufficient antitumor activity to warrant further study in patients with metastatic colorectal cancer.

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1994-06, Vol.86 (12), p.944-945
Main Authors: MARSCHKE, ROBERT F., WIEAND, HARRY S., O'CONNELL, MICHAEL J., RUBIN, JOSEPH, SCHUTT, ALLEN J., BURCH, PATRICK A., KOVACH, JOHN S.
Format: Article
Language:English
Subjects:
Antineoplastic Agents - therapeutic use
Carcinoma - drug therapy
Colon cancer
Colorectal Neoplasms - drug therapy
Drug therapy
Humans
Imides - therapeutic use
Intercalating Agents
Isoquinolines - therapeutic use
Letters to the editor
Naphthalimides
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Description
Summary:A study in which 34 ambulatory patients with measurable, advanced colorectal adenocarcinoma were treated with amonafide is described in a letter to the editor. It was discovered that amonafide has insufficient antitumor activity to warrant further study in patients with metastatic colorectal cancer.
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/86.12.944