Cerebral embolism--first manifestation of pulmonary arteriovenous malformation in patients with hereditary hemorrhagic telangiectasia

Four of five patients with asymptomatic small or moderate-size pulmonary arteriovenous malformation (PAVM) presented with a paradoxical embolus and stroke. In these patients chest radiographic findings were subtle and arterial hypoxemia provided the real clue to diagnosis. Computed tomography (CT) a...

Full description

Saved in:
Bibliographic Details
Published in:Cardiovascular and interventional radiology 1985, Vol.8 (3), p.151-155
Main Authors: Hewes, R C, Auster, M, White, Jr, R I
Format: Article
Language:English
Subjects:
Adult
Arteriovenous Malformations - diagnostic imaging
Arteriovenous Malformations - etiology
Arteriovenous Malformations - therapy
Cerebral Angiography
Embolization, Therapeutic
Female
Humans
Intracranial Embolism and Thrombosis - diagnostic imaging
Intracranial Embolism and Thrombosis - etiology
Male
Middle Aged
Pulmonary Artery - abnormalities
Pulmonary Artery - diagnostic imaging
Pulmonary Veins - abnormalities
Pulmonary Veins - diagnostic imaging
Telangiectasia, Hereditary Hemorrhagic - complications
Tomography, X-Ray Computed
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Four of five patients with asymptomatic small or moderate-size pulmonary arteriovenous malformation (PAVM) presented with a paradoxical embolus and stroke. In these patients chest radiographic findings were subtle and arterial hypoxemia provided the real clue to diagnosis. Computed tomography (CT) and cerebral arteriography confirmed embolic occlusion in four of five patients. Careful family screening including posteroanterior (PA) and lateral chest radiographs and arterial oxygen determinations in sitting or standing positions are recommended for early detection of asymptomatic patients with PAVM. Early therapeutic intervention (with balloon embolotherapy) is recommended to avoid paradoxical embolization.
ISSN:0174-1551
DOI:10.1007/BF02552883