Controlled comparison of nalbuphine and morphine for post‐tonsillectomy pain

Summary A controlled investigation was conducted to compare the effectiveness of morphine and nalbuphine in the prevention of pain and restlessness after tonsillectomy in children. Sixty children between 4 and 12 years old were randomly allocated to receive intramuscular morphine 0.2 mg/kg, nalbuphi...

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Bibliographic Details
Published in:Anaesthesia 1985-12, Vol.40 (12), p.1178-1181
Main Authors: KRISHNAN, A., TOLHURST‐CLEAVER, C. L., KAY, B.
Format: Article
Language:English
Subjects:
Analgesics
Analgesics, narcotic
morphine, nalbuphine
Biological and medical sciences
Child
Child, Preschool
Clinical Trials as Topic
Female
Humans
Male
Medical sciences
Morphinans - therapeutic use
Morphine - therapeutic use
Nalbuphine - therapeutic use
Neuropharmacology
Pain, Postoperative - drug therapy
Pain
postoperative
Pharmacology. Drug treatments
Psychomotor Agitation - drug therapy
Tonsillectomy
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Summary:Summary A controlled investigation was conducted to compare the effectiveness of morphine and nalbuphine in the prevention of pain and restlessness after tonsillectomy in children. Sixty children between 4 and 12 years old were randomly allocated to receive intramuscular morphine 0.2 mg/kg, nalbuphine 0.3 mg/kg or no medication approximately 5 minutes before the conclusion of surgery. Pain and restlessness were assessed 1 and 2 hours after injection, and side effects were recorded. The assessments were made double‐blind. Both nalbuphine and morphine decreased restlessness and pain 1 hour (p
ISSN:0003-2409
1365-2044
DOI:10.1111/j.1365-2044.1985.tb10654.x