Estimation of Ventricular Repolarization in Man by Monophasic Action Potential Recording Technique

Myocardial monophasic action potentials (MAP) can be recorded with the aid of suction or contact electrodes applied endocardially via a catheter. The technique necessitates high input impedance amplifiers with infinite time constant. A bipolar technique improves signal quality with regard to electri...

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Bibliographic Details
Published in:European heart journal 1985-11, Vol.6 (suppl-D), p.71-79
Main Authors: Olsson, S. B., Brorson, L., Edvardsson, N., Varnauskas, E.
Format: Article
Language:English
Subjects:
Cardiac Catheterization
catheterization
Electrocardiography
Electrodes
Endocardium - physiopathology
Heart Atria - physiopathology
Heart Block - physiopathology
Heart Conduction System - physiopathology
Heart Ventricles - physiopathology
Humans
Monophasic action potential
ventricular repolarization
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Summary:Myocardial monophasic action potentials (MAP) can be recorded with the aid of suction or contact electrodes applied endocardially via a catheter. The technique necessitates high input impedance amplifiers with infinite time constant. A bipolar technique improves signal quality with regard to electrical contamination around the rapid upstroke of the MAP. Mechanical artefacts in the recordings are common and may be explained by catheter movement induced by atrial or ventricular contractions. The MAP signal can be used for a precise measurement of time of local excitation and for the study of atrial as well as ventricular repolarization. The technique has mostly been applied in the exploration of atrial and ventricular repolarization in healthy hearts and during different cardiac arrhythmias. Furthermore, several studies have documented the electrophysiological action of antiarrhythmic drugs upon the human heart. Concluding from 576 different investigations we consider the technique to have no serious side-effects.
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/6.suppl_D.71