Negative Bone Scintigraphy With Diffuse Osteoblastic Breast Carcinoma Metastases

A patient with diffuse osteoblastic metastases from invasive lobular carcinoma of the breast is presented in whom radionuclldo bone scan was negative for skeletal lesions. Skeletal metastases were documented by plain radiography, CT, MRI, and bone marrow biopsy. This case report points to the value...

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Bibliographic Details
Published in:Clinical nuclear medicine 1994-03, Vol.19 (3), p.194-196
Main Authors: BROWN, BRADLEY, LAORR, ALAN, GREENSPAN, ADAM, STADALNIK, ROBERT
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Bone and Bones - diagnostic imaging
Bone Neoplasms - diagnosis
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - secondary
Breast Neoplasms - pathology
Carcinoma, Lobular - diagnosis
Carcinoma, Lobular - diagnostic imaging
Carcinoma, Lobular - secondary
Diseases of the osteoarticular system
False Negative Reactions
Female
Humans
Magnetic Resonance Imaging
Medical sciences
Radionuclide Imaging
Technetium Tc 99m Medronate
Tomography, X-Ray Computed
Tumors of striated muscle and skeleton
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Description
Summary:A patient with diffuse osteoblastic metastases from invasive lobular carcinoma of the breast is presented in whom radionuclldo bone scan was negative for skeletal lesions. Skeletal metastases were documented by plain radiography, CT, MRI, and bone marrow biopsy. This case report points to the value of plain-film, CT, and MRI findings in situations of high clinical suspicion of metastatic disease despite a normal scintigraphy.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199403000-00005