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Retro-Binding Tripeptide Thrombin Active-Site Inhibitors: Discovery, Synthesis, and Molecular Modeling

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Published in:	Journal of medicinal chemistry 1994-07, Vol.37 (14), p.2122-2124
Main Authors:	Iwanowicz, Edwin J, Lau, Wan F, Lin, James, Roberts, Daniel G. M, Seiler, Steven M
Format:	Article
Language:	English
Subjects:	Amino Acid Sequence Binding Sites Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Medical sciences Models, Molecular Molecular Sequence Data Oligopeptides - metabolism Pharmacology. Drug treatments Serine Proteinase Inhibitors - chemical synthesis Structure-Activity Relationship Thrombin - antagonists & inhibitors Thrombin - metabolism
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container_issue	14
container_start_page	2122
container_title	Journal of medicinal chemistry
container_volume	37
creator	Iwanowicz, Edwin J Lau, Wan F Lin, James Roberts, Daniel G. M Seiler, Steven M
description
doi_str_mv	10.1021/jm00040a001
format	article
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subjects	Amino Acid Sequence Binding Sites Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Medical sciences Models, Molecular Molecular Sequence Data Oligopeptides - metabolism Pharmacology. Drug treatments Serine Proteinase Inhibitors - chemical synthesis Structure-Activity Relationship Thrombin - antagonists & inhibitors Thrombin - metabolism
title	Retro-Binding Tripeptide Thrombin Active-Site Inhibitors: Discovery, Synthesis, and Molecular Modeling
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