CYTOSTATIN, A NOVEL INHIBITOR OF CELL ADHESION TO COMPONENTS OF EXTRACELLULAR MATRIX PRODUCED BY Streptomyces sp. MJ654-NF4: II. PHYSICO-CHEMICAL PROPERTIES AND STRUCTURE DETERMINATION

The structure of cytostatin was determined to be 5, 6-dihydro-5-methyl-6-(6-hydroxy-1, 5-dimethyl-4-phosphonooxy-7, 9, 11-tridecatrienyl)-2H-pyran-2-one sodium salt on the basis of physico-chemical properties and NMR studies.

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Bibliographic Details
Published in:Journal of antibiotics 1994/05/25, Vol.47(5), pp.541-544
Main Authors: AMEMIYA, MASAHIDE, SOMENO, TETSUYA, SAWA, RYUICHI, NAGANAWA, HIROSHI, ISHIZUKA, MASAAKI, TAKEUCHI, TOMIO
Format: Article
Language:English
Subjects:
Antibiotics, Antineoplastic - chemistry
Biological and medical sciences
Cell Adhesion - drug effects
Chemical Phenomena
Chemistry, Physical
Extracellular Matrix Proteins - metabolism
General pharmacology
Magnetic Resonance Spectroscopy
Medical sciences
Molecular Structure
Organophosphates - chemistry
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Pyrones - chemistry
Streptomyces
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Summary:The structure of cytostatin was determined to be 5, 6-dihydro-5-methyl-6-(6-hydroxy-1, 5-dimethyl-4-phosphonooxy-7, 9, 11-tridecatrienyl)-2H-pyran-2-one sodium salt on the basis of physico-chemical properties and NMR studies.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.47.541