Variability of lipid phenotypes in hyperuricaemic-hyperlipidemic patients

We studied changes in the hyperuricaemia-associated lipid phenotypes of primary hyperuricaemic-hyperlipidemic patients, none of whom was obese, hypertensive or an alcohol drinker. The patients were monitored for three months during which they were placed on a strict diet. The results obtained showed...

Full description

Saved in:
Bibliographic Details
Published in:Clinical rheumatology 1994-06, Vol.13 (2), p.244-247
Main Authors: Collantes, E, Tinahones, F J, Cisnal, A, Añon, J, Sanchez-Guijo, P
Format: Article
Language:English
Subjects:
Adult
Apolipoproteins B - analysis
Female
Humans
Hyperlipidemias - blood
Hyperlipidemias - genetics
Lipids - genetics
Male
Middle Aged
Prospective Studies
Uric Acid - blood
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We studied changes in the hyperuricaemia-associated lipid phenotypes of primary hyperuricaemic-hyperlipidemic patients, none of whom was obese, hypertensive or an alcohol drinker. The patients were monitored for three months during which they were placed on a strict diet. The results obtained showed that phenotype IIB was most frequently associated with hyperuricaemia, followed by phenotypes IV and IIA. Lipid phenotypes were found to change in most patients during the study, even though most of them remained hyperuricaemic-hyperlipidemic. We also determined apoprotein B in each determination and found that over half the patients possessed increased levels of this apolipoprotein. The results confirm that hyperuricaemia is not associated to a unique lipid phenotype since the phenotype of a given patient may change with time, even in the absence of propitiating external factors.
ISSN:0770-3198
1434-9949
DOI:10.1007/BF02249020