Synthesis of a new chemically and metabolically stable prostacyclin analogue with high and long-lasting oral activity

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Bibliographic Details
Published in:Journal of medicinal chemistry 1986-03, Vol.29 (3), p.313-315
Main Authors: SKUBALLA, W, SCHILLINGER, E, STURZEBECHER, C.-S, VORBRUGGEN, H
Format: Article
Language:English
Subjects:
Administration, Oral
Alicyclic compounds, terpenoids, prostaglandins, steroids
Animals
Binding, Competitive
Blood Pressure - drug effects
Chemistry
Epoprostenol - administration & dosage
Epoprostenol - chemical synthesis
Epoprostenol - pharmacology
Exact sciences and technology
Heart Rate - drug effects
Humans
Iloprost
In Vitro Techniques
Organic chemistry
Platelet Aggregation - drug effects
Preparations and properties
Prostaglandins
Rats
Receptors, Epoprostenol
Receptors, Prostaglandin - metabolism
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ISSN:0022-2623
DOI:10.1021/jm00153a001