Bleeding Due to Thrombocytopenia in Acute Leukemias and Reevaluation of the Prophylactic Platelet Transfusion Policy

Prophylactic platelet administration is indicated at counts below 20×109/l. The bleeding tendency and severity were compared between thrombocytopenic patients with acutelymphocytic leukemia (ALL) and acute nonlymphocytic leukemia (ANLL) in the ranges of 10–20×109/1 platelets, while prophylactic plat...

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Bibliographic Details
Published in:The American journal of the medical sciences 1986-03, Vol.291 (3), p.147-151
Main Authors: Aderka, Dan, Praff, Giora, Santo, Moshe, Weinberger, Abraham, Pinkhas, Jack
Format: Article
Language:English
Subjects:
Acute Lymphocytic Leukemia
Acute Myelocytic Leukemia
Adolescent
Adult
Antineoplastic Agents - adverse effects
Antineoplastic Agents - therapeutic use
Biological and medical sciences
Blood Transfusion
Hematologic and hematopoietic diseases
Hemorrhage - etiology
Hemorrhage - prevention & control
Humans
Leukemia, Lymphoid - complications
Leukemia, Lymphoid - drug therapy
Leukemia, Lymphoid - therapy
Leukemia, Myeloid, Acute - complications
Leukemia, Myeloid, Acute - drug therapy
Leukemia, Myeloid, Acute - therapy
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
Platelet Count
Platelet Transfusion
Thrombocytopenia
Thrombocytopenia - etiology
Thrombocytopenia - prevention & control
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Summary:Prophylactic platelet administration is indicated at counts below 20×109/l. The bleeding tendency and severity were compared between thrombocytopenic patients with acutelymphocytic leukemia (ALL) and acute nonlymphocytic leukemia (ANLL) in the ranges of 10–20×109/1 platelets, while prophylactic platelet administration was given only below 10×109/l. The bleeding tendency for ALL was quite similar at platelet counts above or below 10×109/1. The bleeding tendency was significantly lower (p
ISSN:0002-9629
1538-2990
DOI:10.1097/00000441-198603000-00001