Comparative analysis of the gene encoding the nucleocapsid protein of dolphin morbillivirus reveals its distant evolutionary relationship to measles virus and ruminant morbilliviruses

1 Laboratory of Virology and Immunology, The Royal Veterinary and Agricultural University, BÜlowsvej 13, Frederiksberg C, DK-1870, Denmark and 2 Department of Virology, Erasmus University, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands A morbillivirus of uncertain origin recently killed hundreds...

Full description

Saved in:
Bibliographic Details
Published in:Journal of general virology 1994-10, Vol.75 (10), p.2829-2834
Main Authors: Blixenkrone-Moller, Merete, Bolt, Gert, Gottschalck, Elisabeth, Kenter, Marcel
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Base Sequence
Biological and medical sciences
Biological Evolution
Capsid - genetics
Cetacea
DNA Primers
Dolphins - virology
Fundamental and applied biological sciences. Psychology
Genes, Viral
Genetics
Genome, Viral
Measles - genetics
Microbiology
Molecular Sequence Data
morbillivirus
Morbillivirus - genetics
Phylogeny
Polymerase Chain Reaction
Ruminants - virology
Sequence Homology, Amino Acid
Viral Core Proteins - genetics
Virology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:1 Laboratory of Virology and Immunology, The Royal Veterinary and Agricultural University, BÜlowsvej 13, Frederiksberg C, DK-1870, Denmark and 2 Department of Virology, Erasmus University, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands A morbillivirus of uncertain origin recently killed hundreds of Mediterranean dolphins. This is the first report of the nucleotide and deduced amino acid sequence of a dolphin morbillivirus (DMV) gene. The sequence of the nucleocapsid (N) gene including boundaries was determined. When the DMV N gene coding region was compared with the corresponding sequences of other morbilliviruses a distant evolutionary relationship between these viruses and DMV was apparent. Phylogenetic analysis of the sequence data provided further evidence that DMV is not closely related to any known morbillivirus, whereas phocine distemper virus exhibits a relatively close relationship to canine distemper virus. Received 28 March 1994; accepted 16 June 1994.
ISSN:0022-1317
1465-2099
DOI:10.1099/0022-1317-75-10-2829