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Giardiasis in a Group of Travellers — Attempted Use of a Serological Test

A tour group visiting the USSR was exposed to Giardia lamblia. On return, a questionnaire and letter was sent to each member of the group informing them of the exposure and suggesting laboratory investigation. Sera and stools, tested for anti-Giardia immunoglobulin G and for trophozoites and cysts,...

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Published in:Canadian journal of public health 1986-03, Vol.77 (2), p.86-88
Main Authors: ISAAC-RENTON, JUDITH L., BLACK, WILLIAM A., MATHIAS, RICHARD G., PROCTOR, EILEEN M., SHERLOCK, CHRISTOPHER H.
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container_title Canadian journal of public health
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creator ISAAC-RENTON, JUDITH L.
BLACK, WILLIAM A.
MATHIAS, RICHARD G.
PROCTOR, EILEEN M.
SHERLOCK, CHRISTOPHER H.
description A tour group visiting the USSR was exposed to Giardia lamblia. On return, a questionnaire and letter was sent to each member of the group informing them of the exposure and suggesting laboratory investigation. Sera and stools, tested for anti-Giardia immunoglobulin G and for trophozoites and cysts, respectively, were requested. Fifty-three (73%) group members who submitted serum, at least two stools and a completed questionnaire were included in this study; 43 were found to have giardiasis on stool examination. Using a four-hour ELISA technique developed in this laboratory, 15 sera from these stool-positive cases were positive on serological examination. While serological methods may be a useful adjunct in clinical and epidemiological investigations of giardiasis, further developments are necessary before this type of testing will become both practical and useful. Un groupe de personnes a été exposé à la giardiase lamblia lors d'une visite en URSS. Au retour, chaque personne a reçu un questionnaire et une lettre l'informant de cet état de choses, suggéront un examen. On a ainsi demandé le prélèvement de sérums et de selles, afin d'y détectes la présence d'immunoglobuline G anti-Giardia et de trophozoites et de kystes. Cinquante-trois personnes (soit 73 %) ont remis du sérum, deux échantillons de selles et un questionnaire. L'examen des selles a révélé que 43 personnes avaient contracté la giardiase. Étudiés à l'aide de la technique ELISA (4 heures) mise au point dans notre laboratoire, quinze sérums provenant des cas confirmés par l'examen des selles se sont révélés positifs lors du test sérologique. Bien que l'examen sérologique puisse être un complément appréciable lors de recherches cliniques et épidémioligiques concernant la giardiase, Usera nécessaire de la perfectionner si l'on souhaite le rendre pratique et utile.
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identifier ISSN: 0008-4263
ispartof Canadian journal of public health, 1986-03, Vol.77 (2), p.86-88
issn 0008-4263
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source JSTOR Archival Journals and Primary Sources Collection
subjects Adolescent
Adult
Antigens
Enzyme-Linked Immunosorbent Assay
Epidemiology
Evaluation Studies as Topic
Feces - parasitology
Female
Giardia lamblia
Giardiasis
Giardiasis - diagnosis
Giardiasis - etiology
Humans
Immunoglobulins
Infections
Male
Parasitic diseases
Patient assessment
Questionnaires
Serologic tests
Travel
Trophozoites
title Giardiasis in a Group of Travellers — Attempted Use of a Serological Test
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