Thyrotoxicosis-induced Congestive Heart Failure in an Urban Hospital

Thyrotoxicosis has been associated with several cardiac complications, including atrial fibrillation (AF), functional cardiomyopathy, and congestive heart failure (CHE). Thyrotoxicosis-induced CHF has been considered an unusual complication of thyrotoxicosis, occurring generally in older patients. T...

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Bibliographic Details
Published in:The American journal of the medical sciences 1994-12, Vol.308 (6), p.344-348
Main Authors: Wilson, Bruce E., Newmark, Stephen R.
Format: Article
Language:English
Subjects:
Adult
Atrial Fibrillation - etiology
Biological and medical sciences
Congestive heart failure
Endocrinopathies
Female
Heart Failure - etiology
Hemodynamics
Hospitals, Urban
Humans
Male
Medical sciences
Middle Aged
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Thyroid. Thyroid axis (diseases)
Thyrotoxicosis
Thyrotoxicosis - blood
Thyrotoxicosis - complications
Thyrotoxicosis - physiopathology
Thyrotropin - blood
Thyroxine - blood
Ventricular Function, Left
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Summary:Thyrotoxicosis has been associated with several cardiac complications, including atrial fibrillation (AF), functional cardiomyopathy, and congestive heart failure (CHE). Thyrotoxicosis-induced CHF has been considered an unusual complication of thyrotoxicosis, occurring generally in older patients. To determine the nature and frequency of this complication of thyrotoxicosis in an adult, hospitalized population, the authors consecutively evaluated all admissions to a 535-bed urban hospital during a 14-month period. Admitted during the study period were 177 individuals with a principal diagnosis of AF and 21 individuals with a principal diagnosis of thyrotoxicosis. Eleven of these individuals had concomitant AF and thyrotoxicosis, which was 6% of the AF group. Of these 11 patients, 5 had clinically apparent CHF without evidence of other organic heart disease (Group A) and 6 had only AF without clinical CHF (Group B). The 5 patients with CHF had a significantly lower mean age (36) than the 6 with thyrotoxicosis and AF only (P
ISSN:0002-9629
1538-2990
DOI:10.1097/00000441-199412000-00006