Scintigraphic Manifestation of Fibrous Dysplasia

Scintigraphic manifestations of fibrous dysplasia were analyzed in 59 lesions of 26 patients (12 monostotic, 14 polystotic). Bone imaging with Tc-99m MDP revealed a high percentage of increased uptake of radioisotope in the lesions of fibrous dysplasia. Four (14%) of 29 cystic lesions and two (7%) o...

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Bibliographic Details
Published in:Clinical nuclear medicine 1986-06, Vol.11 (6), p.426-429
Main Authors: MACHIDA, KIKUO, MAKITA, KOZO, NISHIKAWA, JUNICHI, OHTAKE, TOHRU, IIO, MASAHIRO
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Child
Child, Preschool
Diseases of the osteoarticular system
Female
Fibrous Dysplasia of Bone - diagnostic imaging
Fibrous Dysplasia, Monostotic - diagnostic imaging
Fibrous Dysplasia, Polyostotic - diagnostic imaging
Humans
Male
Malformations and congenital and or hereditary diseases involving bones. Joint deformations
Medical sciences
Middle Aged
Radionuclide Imaging
Technetium Tc 99m Medronate
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Summary:Scintigraphic manifestations of fibrous dysplasia were analyzed in 59 lesions of 26 patients (12 monostotic, 14 polystotic). Bone imaging with Tc-99m MDP revealed a high percentage of increased uptake of radioisotope in the lesions of fibrous dysplasia. Four (14%) of 29 cystic lesions and two (7%) of 30 lesions with the appearance of ground glass showed no increase in radioisotope uptake, although roentgenograms showed marked changes. Therefore, care must be taken in the diagnosis of fibrous dysplasia with bone imaging alone. Nuclear methods, however, are indispensable in evaluating the dynamic aspects of bone mineral behavior and in demonstrating disease where none was suspected, or in visualizing polyostotic involvement in those cases where only monostotic disease was suspected clinically. It is concluded that both scintigrams and roentgenograms are complementary procedures in the diagnosis of fibrous dysplasia.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-198606000-00015