Serum Cholesterol and Cancer — A Retrospective Case-Control Study

The time relationship between low serum cholesterol and the subsequent development of malignant neoplasms was examined in a case-control study of 100 cases of cancer death and 393 controls. The serum cholesterol levels were followed by repeated blood analysis over a 16-year period. An association be...

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Bibliographic Details
Published in:International journal of epidemiology 1986-06, Vol.15 (2), p.155-159
Main Authors: GERHARDSSON, MARIA, ROSENQVIST, URBAN, AHLBOM, ANDERS, CARLSON, LARS A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiovascular Diseases - blood
Cardiovascular Diseases - mortality
Cholesterol - blood
Epidemiology
Female
Humans
Male
Medical sciences
Middle Aged
Miscellaneous
Neoplasms - blood
Neoplasms - mortality
Public health. Hygiene
Public health. Hygiene-occupational medicine
Retrospective Studies
Risk
Sweden
Time Factors
Tumors
Urban Population
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Summary:The time relationship between low serum cholesterol and the subsequent development of malignant neoplasms was examined in a case-control study of 100 cases of cancer death and 393 controls. The serum cholesterol levels were followed by repeated blood analysis over a 16-year period. An association between low serum cholesterol and cancer death was found particularly for malignant neoplasms of the large intestine and rectum. This relationship diminished 7–16 years prior to death suggesting that the low serum cholesterol levels were an effect of the cancer in an early stage and not vice versa.
ISSN:0300-5771
1464-3685
DOI:10.1093/ije/15.2.155