Determination of the Normal Range of Furosemide Half-Clearance Times When Using Tc-99m MAG3

In radionuclide diuresis renography, furosemide half-clearance times have been established using Tc-99m DTPA but have not been verified when Tc-99m MAG3 is used. One hundred and six consecutive diuretic renograms using Tc-99m MAG3 for the evaluation of unilateral renal abnormalities were assessed. T...

Full description

Saved in:
Bibliographic Details
Published in:Clinical nuclear medicine 1994-10, Vol.19 (10), p.880-882
Main Authors: ROSSLEIGH, MONICA A, THOMAS, MEGAN Y, MOASE, ANNE L
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Child
Female
Furosemide - pharmacokinetics
Half-Life
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Radioisotope Renography - methods
Radionuclide investigations
Reference Values
Technetium Tc 99m Mertiatide
Technetium Tc 99m Pentetate
Urinary system
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In radionuclide diuresis renography, furosemide half-clearance times have been established using Tc-99m DTPA but have not been verified when Tc-99m MAG3 is used. One hundred and six consecutive diuretic renograms using Tc-99m MAG3 for the evaluation of unilateral renal abnormalities were assessed. The furosemide half-clearance times of the normal kidneys were all less than 9.8 minutes, with a mean of 3.4 minutes. In 18 patients, the half-clearance times of the normal kidney were artificially prolonged because urine had drained before the administration of the diuretic. The normal furosemide half-clearance time values obtained using Tc-99m MAG3 were found to be similar to those established for Tc-99m DTPA. Prolonged half-clearance times of Tc-99m MAG3 must be confirmed by visual evidence of obstruction.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-199410000-00008